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Article

A major effect QTL determined by multiple genes in epileptic EL mice.

Genome research - 1 Jan 2000

Legare M E, Bartlett F S, Frankel W N

Abstract excerpt

The EL mouse strain provides a polygenic model for epilepsy. Previous mapping experiments between EL and nonepileptic ABP mice identified, and a congenic strain confirmed, a quantitative trait locus (QTL), El2, which lowered the threshold to seizures induced by gentle rhythmic tossing. To narrow the map interval further we used a nested strategy to analyze a series of recombinants derived from the congenic...

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Identifiers

PMID: 10645948
PMCID: PMC310503

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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