Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A locus on mouse Ch10 influences susceptibility to limbic seizure severity: fine mapping and in silico candidate gene analysis.

Genes, brain, and behavior - 1 Mar 2014

Winawer M R, Klassen T L, Teed S, Shipman M, Leung E H, Palmer A A

Abstract excerpt

Identification of genes contributing to mouse seizure susceptibility can reveal novel genes or pathways that provide insight into human epilepsy. Using mouse chromosome substitution strains and interval-specific congenic strains (ISCS), we previously identified an interval conferring pilocarpine-induced limbic seizure susceptibility on distal mouse chromosome 10 (Ch10). We narrowed the region by generating...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Chromosomes, Human, Pair 12

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Mammalian

Share to Computational Biology

Share to Genetic Loci

Share to Mice, Congenic

Share to Mice, Inbred C57BL

Share to Seizures

Source

Open in PubMed Open full text

Identifiers

PMID: 24373497
DOI: 10.1111/gbb.12116
PMCID: PMC3947448

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A locus on mouse Ch10 influences susceptibility to limbic seizure severity: fine mapping and in silico candidate gene analysis.PMID 24373497Read ↗

Mapping a mouse limbic seizure susceptibility locus on chromosome 10.Semantic proximity Read ↗

Collaborative Cross mice reveal extreme epilepsy phenotypes and genetic loci for seizure susceptibility.Semantic proximity Read ↗

Fine mapping of a seizure susceptibility locus on mouse Chromosome 1: nomination of Kcnj10 as a causative gene.Semantic proximity Read ↗

Fine Mapping of a Dravet Syndrome Modifier Locus on Mouse Chromosome 5 and Candidate Gene Analysis by RNA-Seq.Semantic proximity Read ↗

Mapping quantitative trait loci for seizure response to a GABAA receptor inverse agonist in mice.Semantic proximity Read ↗

Use of chromosome substitution strains to identify seizure susceptibility loci in mice.Semantic proximity Read ↗

Fine Mapping and Candidate Gene Analysis of Dravet Syndrome Modifier Loci on Mouse Chromosomes 7 and 8Semantic proximity Read ↗

Meta-analysis of genetic mapping studies in mice reveals candidate epilepsy modifier genes that are outside the current drug development landscapeSemantic proximity Read ↗

Complex seizure disorder caused by Brunol4 deficiency in mice.Semantic proximity Read ↗

Phenotyping mouse chromosome substitution strains reveal multiple QTLs for febrile seizure susceptibility.Semantic proximity Read ↗

Genetics of complex neurological disease: challenges and opportunities for modeling epilepsy in mice and rats.Semantic proximity Read ↗

Experimental models of multifactorial epilepsies: the EL mouse and mice susceptible to audiogenic seizures.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.