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Article

Mapping loci for pentylenetetrazol-induced seizure susceptibility in mice.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Aug 1999

Ferraro T N, Golden G T, Smith G G, St Jean P, Schork N J, Mulholland N, Ballas C, Schill J, Buono R J, Berrettini W H

Abstract excerpt

DBA/2J (D2) and C57BL/6J (B6) mice exhibit differential sensitivity to seizures induced by various chemical and physical methods, with D2 mice being relatively sensitive and B6 mice relatively resistant. We conducted studies in mature D2, B6, F1, and F2 intercross mice to investigate behavioral seizure responses to pentylenetetrazol (PTZ) and to map the location of genes that influence this trait. Mice were...

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Identifiers

PMID: 10436030
PMCID: PMC6782858

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Source receipt: pubmed, retrieved 7 Sept 2026.

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