Article
Genotyping microsatellite polymorphisms by agarose gel electrophoresis with ethidium bromide staining: application to quantitative trait loci analysis of seizure susceptibility in mice.
Psychiatric genetics - 1 Jan 1998
Ferraro T N, Schill J F, Ballas C, Mulholland N, Golden G T, Smith G G, Buono R J, Berrettini W H
Abstract excerpt
Agarose gel electrophoresis with ethidium bromide staining (AGE/EBS) is an efficient and reliable method for analyzing microsatellite polymorphisms. We report the use of AGE/EBS for analyzing DNA microsatellite polymorphisms in a preliminary quantitative trait loci (QTL) study of seizure suscepti...
Topics
- Animals
- Chromosome Mapping
- Convulsants
- Crosses, Genetic
- DNA
- Drug Resistance
- Electrophoresis, Agar Gel
- Ethidium
- Female
- Fluorescent Dyes
- GABA-A Receptor Antagonists
- Genetic Predisposition to Disease
- Genotype
- Male