Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rat chromosome 19 transfer from SHR ameliorates hypertension, salt-sensitivity, cardiovascular and renal organ damage in salt-sensitive Dahl rats.

Journal of hypertension - 1 Jan 2007

Wendt Norbert, Schulz Angela, Siegel Anja-Kristin, Weiss Judith, Wehland Markus, Sietmann Anika, Kossmehl Peter, Grimm Daniela, Stoll Monika, Kreutz Reinhold

Abstract excerpt

OBJECTIVES: Unlike Dahl salt-sensitive (SS) rats, some strains of spontaneously hypertensive (SHR) rats develop only minor organ damage even when exposed to high-salt diet. In previous linkage studies, we identified quantitative trait loci on rat chromosome 19 (RNO19) linked to the SHR allele suggesting a protective effect against salt-induced hypertensive organ damage in SS. METHODS: To test the relevance of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiomegaly
Share to Chromosomes, Mammalian

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Ventricles

Share to Proteinuria

Share to Rats, Inbred Dahl

Share to Rats, Inbred SHR

Share to Sodium Chloride, Dietary

Share to Ventricular Function, Left

Source

Identifiers

PMID: 17143179
DOI: 10.1097/HJH.0b013e328010688f

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rat chromosome 19 transfer from SHR ameliorates hypertension, salt-sensitivity, cardiovascular and renal organ damage in salt-sensitive Dahl rats.PMID 17143179Read ↗

Genetic analysis of salt-sensitive hypertension in Dahl rats reveals a link between cardiac fibrosis and high cholesterol.Semantic proximity Read ↗

Genetic linkage of albuminuria and renal injury in Dahl salt-sensitive rats on a high-salt diet: comparison with spontaneously hypertensive rats.Semantic proximity Read ↗

Hypertensive renal disease: susceptibility and resistance in inbred hypertensive rat lines.Semantic proximity Read ↗

Genetic loci contribute to the progression of vascular and cardiac hypertrophy in salt-sensitive spontaneous hypertension.Semantic proximity Read ↗

Early onset albuminuria in Dahl rats is a polygenetic trait that is independent from salt loading.Semantic proximity Read ↗

Increased susceptibility to kidney injury by transfer of genomic segment from SHR onto Dahl S genetic background.Semantic proximity Read ↗

Chromosome substitution reveals the genetic basis of Dahl salt-sensitive hypertension and renal disease.Semantic proximity Read ↗

Multiple blood pressure loci on rat chromosome 13 attenuate development of hypertension in the Dahl S hypertensive rat.Semantic proximity Read ↗

Haploinsufficiency of the Transcription Factor Ets-1 Is Renoprotective in Dahl Salt-Sensitive Rats.Semantic proximity Read ↗

Dissection of chromosome 18 blood pressure and salt-sensitivity quantitative trait loci in the spontaneously hypertensive rat.Semantic proximity Read ↗

Time-course genetic analysis of albuminuria in Dahl salt-sensitive rats on low-salt diet.Semantic proximity Read ↗

Narrowing a region on rat chromosome 13 that protects against hypertension in Dahl SS-13BN congenic strains.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.