Article
Hypertensive renal disease: susceptibility and resistance in inbred hypertensive rat lines.
Journal of hypertension - 1 Oct 2013
Braun Michael C, Herring Stacy M, Gokul Nisha, Monita Monique, Bell Rebecca, Hicks M John, Wenderfer Scott E, Doris Peter A
Abstract excerpt
BACKGROUND: Spontaneously hypertensive rat (SHR) lines differ in their susceptibility to hypertensive end-organ disease and may provide an informative model of genetic risk of disease. Lines derived from the original SHR-B and SHR-C clades are highly resistant to hypertensive end-organ disease, whereas lines derived from the SHR-A clade were selected for stroke susceptibility and experience hypertensive renal...
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