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Article

Haploinsufficiency of the Transcription Factor Ets-1 Is Renoprotective in Dahl Salt-Sensitive Rats.

Journal of the American Society of Nephrology : JASN - 1 Nov 2017

Feng Wenguang, Chen Bo, Xing Dongqi, Li Xingsheng, Fatima Huma, Jaimes Edgar A, Sanders Paul W

Abstract excerpt

Studies using Dahl salt-sensitive (SS) rats identified specific quantitative trait loci that predispose animals to hypertension-associated albuminuria and kidney injury. We explored the hypothesis that kidney-specific expression of the transcription factor Ets-1, located within one of these loci on chromosome 8, mediates glomerular injury in SS hypertension. During the first week on a high-salt diet, SS rats and...

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Source

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Identifiers

PMID: 28696249
DOI: 10.1681/ASN.2017010085
PMCID: PMC5661288

Genes

MMP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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