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Article

Chromosome substitution reveals the genetic basis of Dahl salt-sensitive hypertension and renal disease.

American journal of physiology. Renal physiology - 1 Sept 2008

Mattson David L, Dwinell Melinda R, Greene Andrew S, Kwitek Anne E, Roman Richard J, Jacob Howard J, Cowley Allen W

Abstract excerpt

This study examined the genetic basis of hypertension and renal disease in Dahl SS/Mcwi (Dahl Salt-Sensitive) rats using a complete chromosome substitution panel of consomic rats in which each of the 20 autosomes and the X and Y chromosomes were individually transferred from the Brown Norway (BN) rat onto the Dahl SS/Mcwi genetic background. Male and female rats of each of the two parental and 22 consomic strains...

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Source

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Identifiers

PMID: 18653478
DOI: 10.1152/ajprenal.90341.2008
PMCID: PMC2536867

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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