Article
Role of TLR4 receptor polymorphisms in Boutonneuse fever.
International journal of immunopathology and pharmacology - 1 Jan 2000
Balistreri C R, Candore G, Lio D, Colonna-Romano G, Di Lorenzo G, Mansueto P, Rini G, Mansueto S, Cillari E, Franceschi C, Caruso C
Abstract excerpt
The genetics of the interaction between host and microbes plays an essential role in the survival of the individual and attainment of longevity. The activation of toll-like receptor (TLR)4 plays a key role in natural and clonotypic immune responses. We evaluated whether TLR4 genotype is a component of genetic background protective versus rickettsiosis and whether this background influences longevity. We genotyped...
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