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Article

Toll-like receptor 4 (TLR4) and typhoid fever in Vietnam.

PloS one - 1 Jan 2009

Nguyen Thi Hue, Mai Ngoc Lanh, Le Thi Phuong, Ha Vinh, Nguyen Tran Chinh, Tran Tinh Hien, Nguyen T Hieu, Farrar Jeremy J, Dunstan Sarah J

Abstract excerpt

Understanding the host genetic susceptibility to typhoid fever may provide a better understanding of pathogenesis and help in the development of new therapeutics and vaccines. Here we determine the genetic variation within the human TLR4 gene encoding the principal receptor for bacterial endotoxin recognition in typhoid fever patients. It is possible that genetic variants of TLR4 could detrimentally affect the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19277200
DOI: 10.1371/journal.pone.0004800
PMCID: PMC2652111

Genes

TLR4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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