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Article

TLR2 and TLR4 polymorphisms in familial Mediterranean fever.

Human immunology - 1 Sept 2009

Speletas Matthaios, Kalala Fani, Mitroulis Ioannis, Papadopoulos Vassileios, Merentiti Vassiliki, Germenis Anastasios E, Ritis Konstantinos

Abstract excerpt

It has been suggested that MEVF mutations offer advantage against infections, including tuberculosis. Bearing in mind the central role of TLR-2 and TLR-4 in the recognition of pathogens, we conducted this study to examine whether the TLR2-R753Q, TLR4-D299G, TLR4-T399I common polymorphisms are associated with susceptibility to familial Mediterranean fever (FMF) or affect the course of the disease. A cohort of 169...

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Source

Identifiers

PMID: 19445990
DOI: 10.1016/j.humimm.2009.05.004

Genes

TLR4
TLR2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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