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Article

Regulation of telomere length by an N-terminal region of the yeast telomerase reverse transcriptase.

Molecular and cellular biology - 1 Oct 2005

Ji Hong, Platts Margaret H, Dharamsi Latif M, Friedman Katherine L

Abstract excerpt

Telomerase is a reverse transcriptase that maintains chromosome integrity through synthesis of repetitive telomeric sequences on the ends of eukaryotic chromosomes. In the yeast Saccharomyces cerevisiae, telomere length homeostasis is achieved through negative regulation of telomerase access to the chromosome terminus by telomere-bound Rap1 protein and its binding partners, Rif1p and Rif2p, and positive...

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Identifiers

PMID: 16199886
DOI: 10.1128/MCB.25.20.9103-9114.2005
PMCID: PMC1265764

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Regulation of telomere length by an N-terminal region of the yeast telomerase reverse transcriptase.PMID 16199886Read ↗

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