Article
Intrachromatid excision of telomeric DNA as a mechanism for telomere size control in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Oct 2001
Bucholc M, Park Y, Lustig A J
Abstract excerpt
We have previously identified a process in the yeast Saccharomyces cerevisiae that results in the contraction of elongated telomeres to wild-type length within a few generations. We have termed this process telomeric rapid deletion (TRD). In this study, we use a combination of physical and genetic assays to investigate the mechanism of TRD. First, to distinguish among several recombinational and nucleolytic...
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