Article
A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae.
Genes & development - 15 Mar 1997
Wotton D, Shore D
Abstract excerpt
The Saccharomyces cerevisiae Rap1 protein binds with high affinity to sites within the poly(C(1-3)A) tracts at telomeres, where it plays a role in both telomere length regulation and the initiation of telomeric silencing. Rap1p initiates silencing at telomeres by interacting through its carboxy-t...
Topics
- Bacterial Proteins
- Binding Sites
- Carrier Proteins
- Chromosomes, Fungal
- DNA-Binding Proteins
- Fungal Proteins
- GTP-Binding Proteins
- Membrane Proteins
- Models, Biological
- Mutation
- Recombinant Fusion Proteins
- Repressor Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Telomere
- Telomere-Binding Proteins
- rap GTP-Binding Proteins