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Article

Telomerase, the recombination machinery and Rap1 play redundant roles in yeast telomere protection.

Current genetics - 1 Feb 2021

Kabaha Majdi M, Tzfati Yehuda

Abstract excerpt

Telomeres are specialized nucleoprotein complexes that protect the ends of eukaryotic chromosomes and distinguish them from broken DNA ends. Disruption of telomere protection may cause aging-associated pathologies and cancer. Here, we examined what makes telomere protection durable and resistant to perturbations using a budding yeast model organism. The protein Rap1 binds the telomeric repeats, negatively...

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Identifiers

PMID: 33156376
DOI: 10.1007/s00294-020-01125-4

Genes

RAD52

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Telomerase, the recombination machinery and Rap1 play redundant roles in yeast telomere protection.PMID 33156376Read ↗

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