Article
Telomeric protein distributions and remodeling through the cell cycle in Saccharomyces cerevisiae.
Molecular biology of the cell - 1 Feb 2003
Smith C D, Smith D L, DeRisi J L, Blackburn E H
Abstract excerpt
In Saccharomyces cerevisiae, telomeric DNA is protected by a nonnucleosomal protein complex, tethered by the protein Rap1. Rif and Sir proteins, which interact with Rap1p, are thought to have further interactions with conventional nucleosomic chromatin to create a repressive structure that protects the chromosome end. We showed by microarray analysis that Rif1p association with the chromosome ends extends to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.