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Article

Flow cytometric assay for determination of FcgammaRIIIA-158 V/F polymorphism.

Journal of immunological methods - 30 Nov 2005

Böttcher Sebastian, Ritgen Matthias, Brüggemann Monika, Raff Thorsten, Lüschen Silke, Humpe Andreas, Kneba Michael, Pott Christiane

Abstract excerpt

A single nucleotide polymorphism (SNP) of the FCGR3A gene results in two allotypes of Fcgamma receptor IIIA (FcgammaRIIIA) with valine (V) or phenylalanine (F) at amino acid 158. Since the FcgammaRIIIA-158 V/F polymorphism is associated with the efficacy of monoclonal antibody (mAb) treatment and a risk factor for autoimmune disease, widely applicable methods to assess the SNP are needed. We developed a novel...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16181633
DOI: 10.1016/j.jim.2005.08.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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