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Article

A novel PCR-based method for direct Fc gamma receptor IIIa (CD16) allotyping.

Journal of immunological methods - 28 Aug 2000

Leppers-van de Straat F G, van der Pol W L, Jansen M D, Sugita N, Yoshie H, Kobayashi T, van de Winkel J G

Abstract excerpt

Leukocyte IgG receptors (Fc gamma R) are important immune-response modulating molecules. Fc gamma RIIIa is expressed on macrophages, NK-cells and gamma delta-T cells and exhibits a genetically determined, functional polymorphism at nucleotide 559. This allelic difference predicts either a phenylalanine (F158) or valine (V158) at amino acid 158 in the membrane-proximal extracellular domain, and has been shown to...

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PMID: 10986395
DOI: 10.1016/s0022-1759(00)00240-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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