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Article

FcγRIIIa-158V/F polymorphism affects the performance of FcγRIIIa-related bioassay.

Biochemical and biophysical research communications - 11 Jun 2022

Aoyama Michihiko, Tada Minoru, Ishii-Watabe Akiko

Abstract excerpt

Bioassays are important for estimating biosimilarity between biological products. Comparability studies including bioassays are needed to demonstrate that a biosimilar product has no meaningful differences that affect safety and efficacy compared with the reference product. Among the most important biological characteristics of therapeutic mAbs are Fc-mediated functions, which induce immune-cell activation which...

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Share to Antibodies, Monoclonal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35398612
DOI: 10.1016/j.bbrc.2022.04.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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