Article
Rapid single-step FCGR3A genotyping based on SYBR Green I fluorescence in real-time multiplex allele-specific PCR.
Journal of immunological methods - 1 Jun 2003
Dall'Ozzo Sébastien, Andres Christian, Bardos Pierre, Watier Hervé, Thibault Gilles
Abstract excerpt
A polymorphism at position 559 in the cDNA of the FCGR3A gene encoding the FcgammaRIIIa generates two allotypes with either a valine (Val) or a phenylalanine (Phe) at amino acid position 158. This polymorphism is of major importance in immunopathology and in pharmacogenetics, especially monoclona...
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