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Article

Association of myeloperoxidase promotor polymorphism with cirrhosis in patients with hereditary hemochromatosis.

Journal of hepatology - 1 Jun 2005

Osterreicher Christoph H, Datz Christian, Stickel Felix, Hellerbrand Claus, Penz Melitta, Hofer Harald, Wrba Fritz, Penner Edward, Schuppan Detlef, Ferenci Peter

Abstract excerpt

BACKGROUND/AIMS: Hereditary hemochromatosis (HHC) is a disorder of iron metabolism with variable penetrance. Oxidative stress plays a central role in the progression to cirrhosis. Several enzymes involved in the production or degradation of reactive oxidants, like myeloperoxidase (MPO) and heme oxygenase (HO)-1 are influenced by promotor polymorphisms. This study assessed the impact of polymorphisms of the MPO...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15885363
DOI: 10.1016/j.jhep.2005.01.023

Genes

MPO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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