Article
Plasma myeloperoxidase levels correlate with hepatocellular carcinoma in chronic hepatitis C.
Human immunology - 1 Nov 2012
do Carmo Rodrigo Feliciano, de Almeida Débora Bezerra, Aroucha Dayse Célia Barbosa Lins, Vasconcelos Luydson Richardson Silva, de Moraes Adriano Claudio Pereira, de Mendonça Cavalcanti Maria do Socorro, de Morais Clarice Neuenschwander Lins, Pereira Leila Maria Moreira Beltrão, Moura Patrícia
Abstract excerpt
Myeloperoxidase (MPO) is an enzyme responsible for generating hypochlorous acid and reactive oxidants that may lead to liver injury and cancer in hepatitis C (HCV) infection. MPO expression level is regulated by a polymorphism in the promoter region -463 of MPO gene. In the current study, MPO plasma levels and the G-463A MPO polymorphism were determined in 158 chronically HCV infected patients with and without...
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