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Article

Myeloperoxidase and superoxide dismutase 2 polymorphisms comodulate the risk of hepatocellular carcinoma and death in alcoholic cirrhosis.

Hepatology (Baltimore, Md.) - 1 Nov 2009

Nahon Pierre, Sutton Angela, Rufat Pierre, Ziol Marianne, Akouche Hassan, Laguillier Christelle, Charnaux Nathalie, Ganne-Carrié Nathalie, Grando-Lemaire Véronique, N'Kontchou Gisèle, Trinchet Jean-Claude, Gattegno Liliane, Pessayre Dominique, Beaugrand Michel

Abstract excerpt

UNLABELLED: Alcohol increases reactive oxygen species (ROS) formation in hepatocyte mitochondria and by reduced nicotinamide adenine dinucleotide phosphate oxidases and myeloperoxidase (MPO) in Kupffer cells and liver-infiltrating neutrophils. Manganese superoxide dismutase (MnSOD) converts super...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19731237
DOI: 10.1002/hep.23187

Genes

MPO
SOD2
CAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19731237-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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