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Article

- 174 G>C IL-6 polymorphism and primary iron overload in male patients.

Annals of hematology - 1 Sept 2018

Tetzlaff Walter F, Meroño Tomás, Botta Eliana E, Martín Maximiliano E, Sorroche Patricia B, Boero Laura E, Castro Marcelo, Frechtel Gustavo D, Rey Jorge, Daruich Jorge, Cerrone Gloria E, Brites Fernando

Abstract excerpt

Primary iron overload (IO) is commonly associated with mutations in the hereditary hemochromatosis gene (HFE). Nonetheless, other genetic variants may influence the development of IO beyond HFE mutations. There is a single nucleotide polymorphism (SNP) at - 174 G>C of the interleukin (IL)-6 gene which might be associated with primary IO. Our aim was to study the association between the SNP - 174 G>C gene promoter...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29656314
DOI: 10.1007/s00277-018-3333-6

Genes

HFE

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