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Article

Myeloperoxidase promotor polymorphism and risk of hepatoblastoma.

International journal of cancer - 20 Aug 2003

Pakakasama Samart, Chen Tina T-L, Frawley William, Muller Carolyn, Douglass Edwin C, Tomlinson Gail E

Abstract excerpt

Myeloperoxidase (MPO) is a major enzyme found in neutrophils. Oxidation by MPO produces free radicals that demonstrate genotoxic properties. A polymorphism (G to A) within the promotor region of the MPO gene reduces transcription and expression. This polymorphism is associated with a protective effect against some cancers in adults including lung cancer. The objective of our study was to investigate the effect of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12800195
DOI: 10.1002/ijc.11191

Genes

MPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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