Article
Transforming growth factor-β and toll-like receptor-4 polymorphisms are not associated with fibrosis in haemochromatosis.
World journal of gastroenterology - 28 Dec 2013
Wood Marnie J, Powell Lawrie W, Dixon Jeannette L, Subramaniam V Nathan, Ramm Grant A
Abstract excerpt
AIM: To investigate the role of genetic polymorphisms in the progression of hepatic fibrosis in hereditary haemochromatosis. METHODS: A cohort of 245 well-characterised C282Y homozygous patients with haemochromatosis was studied, with all subjects having liver biopsy data and DNA available for testing. This study assessed the association of eight single nucleotide polymorphisms (SNPs) in a total of six genes...
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