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Article

Do genetic variations in antioxidant enzymes influence the course of hereditary hemochromatosis?

Antioxidants & redox signaling - 1 Jul 2011

Nahon Pierre, Sutton Angela, Pessayre Dominique, Rufat Pierre, Charnaux Nathalie, Trinchet Jean-Claude, Beaugrand Michel, Deugnier Yves

Abstract excerpt

Iron-induced oxidative stress promotes hepatic injury in hereditary hemochromatosis, which can be influenced by genetic traits affecting antioxidant enzymes. We assessed the influence of Ala16Val-superoxide dismutase 2, Pro198Leu-glutathione peroxidase 1, and -463G/A-myeloperoxidase genotypes (hi...

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Source

Identifiers

PMID: 20673159
DOI: 10.1089/ars.2010.3529

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20673159-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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