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Article

Myeloperoxidase gene polymorphism predicts fibrosis severity in women with hepatitis C.

Human immunology - 1 Aug 2014

do Carmo Rodrigo Feliciano, Vasconcelos Luydson Richardson Silva, Mendonça Taciana Furtado, de Mendonça Cavalcanti Maria do Socorro, Pereira Leila Maria Moreira Beltrão, Moura Patrícia

Abstract excerpt

Oxidative stress plays an important role on liver fibrosis progression in the course of hepatitis C virus (HCV) infection. Myeloperoxidase (MPO) is an enzyme released by neutrophils and macrophages, responsible for generating hypochlorous acid and reactive oxygen species (ROS) that may lead to liver injury in HCV infection. On the other hand, antioxidant enzymes such as manganese superoxide dismutase (SOD)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24882572
DOI: 10.1016/j.humimm.2014.05.008

Genes

MPO
SOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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