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Article

Crystal structure and interactions of the PAS repeat region of the Drosophila clock protein PERIOD.

Molecular cell - 7 Jan 2005

Yildiz Ozkan, Doi Masao, Yujnovsky Irene, Cardone Luca, Berndt Alex, Hennig Sven, Schulze Sabrina, Urbanke Claus, Sassone-Corsi Paolo, Wolf Eva

Abstract excerpt

PERIOD proteins are central components of the Drosophila and mammalian circadian clock. Their function is controlled by daily changes in synthesis, cellular localization, phosphorylation, degradation, as well as specific interactions with other clock components. Here we present the crystal structure of a Drosophila PERIOD (dPER) fragment comprising two tandemly organized PAS (PER-ARNT-SIM) domains (PAS-A and...

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Source

Identifiers

PMID: 15629718
DOI: 10.1016/j.molcel.2004.11.022

Genes

ARNT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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