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Article

PERspective on PER phosphorylation.

Genes & development - 1 Jul 2008

Blau Justin

Abstract excerpt

Period (PER) proteins are essential parts of the molecular clocks that control circadian rhythms in flies and mammals. Phosphorylation regulates PER's stability and subcellular localization; however, the physiologically relevant sites have been difficult to identify in spite of knowing the relevant kinase. In this issue of Genes & Development, Chiu and colleagues (1758-1772) identify a key phosphorylation site on...

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Identifiers

PMID: 18593875
DOI: 10.1101/gad.1696408
PMCID: PMC2732424

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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PERspective on PER phosphorylation.PMID 18593875Read ↗

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The phospho-occupancy of an atypical SLIMB-binding site on PERIOD that is phosphorylated by DOUBLETIME controls the pace of the clock.Semantic proximity Read ↗

Identification of Light-Sensitive Phosphorylation Sites on PERIOD That Regulate the Pace of Circadian Rhythms in Drosophila.Semantic proximity Read ↗

YIPPEE/YPEL5 regulates circadian period by modulating PER ubiquitination and stabilitySemantic proximity Read ↗

The F-box protein slimb controls the levels of clock proteins period and timeless.Semantic proximity Read ↗

Modelling the dual role of Per phosphorylation and its effect on the period and phase of the mammalian circadian clock.Semantic proximity Read ↗

Differential effects of PER2 phosphorylation: molecular basis for the human familial advanced sleep phase syndrome (FASPS).Semantic proximity Read ↗

Role of phosphorylation in the mammalian circadian clock.Semantic proximity Read ↗

Reversible protein phosphorylation regulates circadian rhythms.Semantic proximity Read ↗

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Endogenous circadian reporters reveal critical consequences of diverse novel mutations in clock genesSemantic proximity Read ↗

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