Article
The mPer2 gene encodes a functional component of the mammalian circadian clock.
Nature - 8 Jul 1999
Zheng B, Larkin D W, Albrecht U, Sun Z S, Sage M, Eichele G, Lee C C, Bradley A
Abstract excerpt
Circadian rhythms are driven by endogenous biological clocks that regulate many biochemical, physiological and behavioural processes in a wide range of life forms. In mammals, there is a master circadian clock in the suprachiasmatic nucleus of the anterior hypothalamus. Three putative mammalian homologues (mPer1, mPer2 and mPer3) of the Drosophila circadian clock gene period (per) have been identified. The mPer...
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