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Article

A simple model of circadian rhythms based on dimerization and proteolysis of PER and TIM.

Biophysical journal - 1 Nov 1999

Tyson J J, Hong C I, Thron C D, Novak B

Abstract excerpt

Many organisms display rhythms of physiology and behavior that are entrained to the 24-h cycle of light and darkness prevailing on Earth. Under constant conditions of illumination and temperature, these internal biological rhythms persist with a period close to 1 day ("circadian"), but it is usually not exactly 24h. Recent discoveries have uncovered stunning similarities among the molecular circuitries of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 20540926
DOI: 10.1016/S0006-3495(99)77078-5
PMCID: PMC1300518

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A simple model of circadian rhythms based on dimerization and proteolysis of PER and TIM.PMID 20540926Read ↗

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Post-translational regulation and nuclear entry of TIMELESS and PERIOD are affected in new timeless mutant.Semantic proximity Read ↗

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