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Article

Oct-3/4 and Sox2 regulate Oct-3/4 gene in embryonic stem cells.

The Journal of biological chemistry - 18 Feb 2005

Okumura-Nakanishi Sayaka, Saito Motoki, Niwa Hitoshi, Ishikawa Fuyuki

Abstract excerpt

Oct-3/4 is a key transcriptional factor whose expression level governs the fate of primitive inner cell mass and embryonic stem (ES) cells. Previously, an upstream 3.3-kb distal enhancer (DE) fragment was identified to be responsible for the specific expression of mouse Oct-3/4 in the inner cell mass and ES cells. However, little is known about the cis-elements and trans-factors required for DE activity. In this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15557334
DOI: 10.1074/jbc.M410015200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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