Article
Isolation, characterization, and differential expression of the murine Sox-2 promoter.
Gene - 4 Apr 2000
Wiebe M S, Wilder P J, Kelly D, Rizzino A
Abstract excerpt
Sox proteins are expressed at many stages of development and in numerous tissues. The transcription factor Sox-2 is first expressed throughout the inner cell mass and subsequently becomes localized to the primitive ectoderm, developing central nervous system, and the lens. Sox-2 is also highly expressed in F9 embryonal carcinoma cells, but becomes undetectable following differentiation of these cells. In this...
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