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Article

Stimulation of Oct‐4 Activity by Ewing's Sarcoma Protein

25 May 2005

Abstract excerpt

The Oct-4 gene encodes a transcription factor that is expressed in embryonic stem (ES) cells and germ cells. Oct-4 is known to function as a transcriptional activator of genes involved in maintaining an undifferentiated totipotent state and possibly in preventing expression of genes activated during differentiation. In addition, it is a putative proto-oncogene and a critical player in the genesis of human...

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PMID: 15917470
DOI: 10.1634/stemcells.2004-0375

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