Article
SOX6 binds CtBP2 to repress transcription from the Fgf-3 promoter.
Nucleic acids research - 15 Aug 2001
Murakami A, Ishida S, Thurlow J, Revest J M, Dickson C
Abstract excerpt
Fgf-3 is expressed in a complex pattern during mouse development. Previously, an essential regulatory element PS4A was identified in the promoter region, and shown to bind at least three factors. To identify the transcription factor(s), we used a yeast one-hybrid screen and obtained a novel Sox6 cDNA (SOX6D). When introduced into cells it strongly repressed activity from both an Fgf-3 reporter gene as well as an...
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