Article
Transcriptional regulation of OCT4 by the ETS transcription factor ESE-1 in NCCIT human embryonic carcinoma cells.
Biochemical and biophysical research communications - 25 Jul 2014
Park Sung-Won, Do Hyun-Jin, Ha Woo Tae, Han Mi-Hee, Yang Heung-Mo, Lee Soo-Hong, Song Hyuk, Kim Nam-Hyung, Kim Jae-Hwan
Abstract excerpt
The epithelium-specific ETS transcription factor-1 (ESE-1) is physiologically important in the pathogenesis of various diseases. Recently, OCT4, a transcription factor involved in stem cell pluripotency, has been implicated in tumorigenesis. In this study, we invested the molecular mechanism by which ESE-1 regulates transcription of OCT4 in NCCIT human embryonic carcinoma cells. Real-time PCR analysis revealed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
