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Heterogeneous DNA methylation status of the regulatory element of the mouse Oct4 gene in adult somatic cell population.

Cloning and stem cells - 1 Jan 2005

Marikawa Yusuke, Fujita Toko C, Alarcón Vernadeth B

Abstract excerpt

The transcription factor Oct4 is specifically expressed in the germ line and pluripotent stem cells, and is indispensable for normal mouse development. To understand the epigenetic control of Oct4 expression, we examined the DNA methylation pattern of the Oct4 regulatory element in various types of cells. Bisulfite analysis showed that the regulatory element was unmethylated in P19 embryonal carcinoma cells,...

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PMID: 15996113
DOI: 10.1089/clo.2005.7.8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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