Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of putative cis-regulatory elements that control the transcriptional activity of the human Oct4 promoter.

Journal of cellular biochemistry - 1 Nov 2005

Yang Heung-Mo, Do Hyun-Jin, Oh Jong-Hyun, Kim Jin-Hoi, Choi Sang-Yun, Cha Kwang-Yul, Chung Hyung-Min, Kim Jae-Hwan

Abstract excerpt

Octamer-binding transcription factor-4 (Oct4), a member of the POU domain transcription factors, is crucial for both early embryonic development and the maintenance of stem cell pluripotency. The human Oct4 (hOct4) 5' upstream sequence contains four conserved regions (CR1, 2, 3, 4) that are homologous in the murine. In this study, we constructed a series of deletion mutants of the hOct4 5' upstream region and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to GC Rich Sequence
Share to Genes, Reporter

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nuclear Proteins

Share to Octamer Transcription Factor-3

Share to Regulatory Sequences, Nucleic Acid

Share to Sequence Alignment

Share to Sp1 Transcription Factor

Share to Sp3 Transcription Factor

Source

Identifiers

PMID: 16149048
DOI: 10.1002/jcb.20588

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of putative cis-regulatory elements that control the transcriptional activity of the human Oct4 promoter.PMID 16149048Read ↗

The expression of the embryonic gene Cripto-1 is regulated by OCT4 in human embryonal carcinoma NCCIT cells.Semantic proximity Read ↗

A consensus Oct1 binding site is required for the activity of the Xenopus Cdx4 promoter.Semantic proximity Read ↗

Promoter analysis of the rabbit POU5F1 gene and its expression in preimplantation stage embryosSemantic proximity Read ↗

Transcriptional regulation of OCT4 by the ETS transcription factor ESE-1 in NCCIT human embryonic carcinoma cells.Semantic proximity Read ↗

Stimulation of Oct‐4 Activity by Ewing's Sarcoma ProteinSemantic proximity Read ↗

Phosphorylation regulates human OCT4.Semantic proximity Read ↗

Oct-3/4 and Sox2 regulate Oct-3/4 gene in embryonic stem cells.Semantic proximity Read ↗

Hypoxia induces CD133 expression in human lung cancer cells by up-regulation of OCT3/4 and SOX2Semantic proximity Read ↗

A far-upstream Oct-1 motif regulates cytokine-induced transcription of the human inducible nitric oxide synthase gene.Semantic proximity Read ↗

Evaluation of regulatory genetic variants in POU5F1 and risk of congenital heart disease in Han Chinese.Semantic proximity Read ↗

Conserved cysteine residues of Oct-2 POU domain confer sensitivity to oxidation but are dispensable for sequence-specific DNA binding.Semantic proximity Read ↗

Characterization of NOBOX DNA Binding Specificity and Its Regulation of Gdf9 and Pou5f1 PromotersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.