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Article

Spatially precise DNA bending is an essential activity of the sox2 transcription factor.

The Journal of biological chemistry - 14 Dec 2001

Scaffidi P, Bianchi M E

Abstract excerpt

Sox proteins, a subclass of high mobility group box proteins, govern cell fate decisions by acting both as classical transcription factors and architectural components of chromatin. We aimed to demonstrate that the DNA bending activity of Sox proteins is essential to regulate gene expression. We focused on mouse Sox2, which participates in the transactivation of the Fgf4 (fibroblast growth factor 4) gene in the...

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Share to Fibroblast Growth Factors
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enhancer Elements, Genetic

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Source

Identifiers

PMID: 11584012
DOI: 10.1074/jbc.M107619200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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