Article
Phenotypic analyses of mouse embryos with ubiquitous expression of Oct4: effects on mid-hindbrain patterning and gene expression.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jan 2005
Ramos-Mejía Verónica, Escalante-Alcalde Diana, Kunath Tilo, Ramírez Laura, Gertsenstein Marina, Nagy Andras, Lomelí Hilda
Abstract excerpt
Oct4 is a transcription factor that has been associated with pluripotency and fate determination in the initial cell lineages of mammals. On the other hand, Pou2, the ortholog of Oct4 in zebrafish, serves additional later functions during brain development acting as a differentiation switch. In m...
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