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Article

Transcriptional regulation of nanog by OCT4 and SOX2.

The Journal of biological chemistry - 1 Jul 2005

Rodda David J, Chew Joon-Lin, Lim Leng-Hiong, Loh Yuin-Han, Wang Bei, Ng Huck-Hui, Robson Paul

Abstract excerpt

Nanog, Sox2, and Oct4 are transcription factors all essential to maintaining the pluripotent embryonic stem cell phenotype. Through a cooperative interaction, Sox2 and Oct4 have previously been described to drive pluripotent-specific expression of a number of genes. We now extend the list of Sox2-Oct4 target genes to include Nanog. Within the Nanog proximal promoter, we identify a composite sox-oct cis-regulatory...

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Source

Identifiers

PMID: 15860457
DOI: 10.1074/jbc.M502573200

Genes

SOX2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Transcriptional regulation of nanog by OCT4 and SOX2.PMID 15860457Read ↗

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