Article
Regulatory function of whey acidic protein in the proliferation of mouse mammary epithelial cells in vivo and in vitro.
Developmental biology - 1 Oct 2004
Nukumi Naoko, Ikeda Kayoko, Osawa Megumi, Iwamori Tokuko, Naito Kunihiko, Tojo Hideaki
Abstract excerpt
Although possible biological functions of whey acidic protein (WAP) have been suggested, few studies have focused on investigating the function of WAP. This paper describes evidence for WAP function in lobulo-alveolar development in mammary glands in vivo and in the cell cycle progression of mammary epithelial cells in vitro. Ubiquitous overexpression of WAP transgene impaired only lobulo-alveolar development in...
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