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Article

The carboxy-terminal domain of human surfactant protein B is not required for secretion in milk of transgenic mice.

Frontiers in bioscience : a journal and virtual library - 1 May 1997

Yarus S, Weaver T E, Rosen J M

Abstract excerpt

Previous studies in which human pulmonary surfactant protein B (SP-B) was targeted to the mammary gland of transgenic mice using the rat whey acidic protein (WAP) regulatory sequences resulted in secretion of only the unprocessed proprotein (42 kDa) in milk. To test the feasibility of producing a partially processed SP-B protein in milk, a new construct was designed in which the coding region for the...

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Identifiers

PMID: 9206990
DOI: 10.2741/a155

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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