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Article

The C/EBPbeta transcription factor regulates epithelial cell proliferation and differentiation in the mammary gland.

Genes & development - 15 Jun 1998

Robinson G W, Johnson P F, Hennighausen L, Sterneck E

Abstract excerpt

Studies of C/EBPbeta-deficient mice have demonstrated a pivotal role for this transcription factor in hematopoiesis, adipogenesis, and ovarian function. Here we show that C/EBPbeta is also essential for normal development and function of the mammary gland. Ductal morphogenesis in virgin C/EBPbeta-deficient mice was disrupted, with ducts displaying reduced growth and branching. To distinguish whether the effect of...

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Identifiers

PMID: 9637691
DOI: 10.1101/gad.12.12.1907
PMCID: PMC316915

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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