The C/EBPbeta transcription factor regulates epithelial cell proliferation and differentiation in the mammary gland.

doi:10.1101/gad.12.12.1907

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Article

The C/EBPbeta transcription factor regulates epithelial cell proliferation and differentiation in the mammary gland.

Genes & development - 15 Jun 1998

Robinson G W, Johnson P F, Hennighausen L, Sterneck E

Abstract excerpt

Studies of C/EBPbeta-deficient mice have demonstrated a pivotal role for this transcription factor in hematopoiesis, adipogenesis, and ovarian function. Here we show that C/EBPbeta is also essential for normal development and function of the mammary gland. Ductal morphogenesis in virgin C/EBPbeta...

Topics

Animals
CCAAT-Enhancer-Binding Proteins
Cell Differentiation
Cell Division
DNA-Binding Proteins
Epithelial Cells
Epithelium
Female
Gene Expression
Genes
Male
Mammary Glands, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Inbred C57BL

Mice, Inbred Strains

Mice, Mutant Strains

Milk Proteins

Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 9637691
DOI: 10.1101/gad.12.12.1907
PMCID: PMC316915

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9637691-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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