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Article

Null mutation of peroxisome proliferator-activated receptor-interacting protein in mammary glands causes defective mammopoiesis.

The Journal of biological chemistry - 6 Aug 2004

Qi Chao, Kashireddy Papreddy, Zhu Yiwei Tony, Rao Sambasiva M, Zhu Yi-Jun

Abstract excerpt

To investigate the role of nuclear receptor coactivator peroxisome proliferator-activated receptor-interacting protein (PRIP) in mammary gland development, we generated a conditional null mutation of PRIP in mammary glands. In PRIP-deficient mammary glands, the elongation of ducts during puberty was not affected, but the numbers of ductal branches were decreased, a condition that persisted long after puberty,...

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Identifiers

PMID: 15161927
DOI: 10.1074/jbc.M401266200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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