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Article

Tcf3: a transcriptional regulator of axis induction in the early embryo.

Development (Cambridge, England) - 1 Jan 2004

Merrill Bradley J, Pasolli H Amalia, Polak Lisa, Rendl Michael, García-García Maria J, Anderson Kathryn V, Fuchs Elaine

Abstract excerpt

The roles of Lef/Tcf proteins in determining cell fate characteristics have been described in many contexts during vertebrate embryogenesis, organ and tissue homeostasis, and cancer formation. Although much of the accumulated work on these proteins involves their ability to transactivate target genes when stimulated by beta-catenin, Lef/Tcf proteins can repress target genes in the absence of stabilized...

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PMID: 14668413
DOI: 10.1242/dev.00935

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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