Article
An embryonic system to assess direct and indirect Wnt transcriptional targets.
Scientific reports - 11 Sept 2017
Suresh Jahnavi, Harmston Nathan, Lim Ka Keat, Kaur Prameet, Jin Helen Jingshu, Lusk Jay B, Petretto Enrico, Tolwinski Nicholas S
Abstract excerpt
During animal development, complex signals determine and organize a vast number of tissues using a very small number of signal transduction pathways. These developmental signaling pathways determine cell fates through a coordinated transcriptional response that remains poorly understood. The Wnt pathway is involved in a variety of these cellular functions, and its signals are transmitted in part through a...
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