Article
Wnt3a links left-right determination with segmentation and anteroposterior axis elongation.
Development (Cambridge, England) - 1 Dec 2005
Nakaya Masa-aki, Biris Kristin, Tsukiyama Tadasuke, Jaime Shaulan, Rawls J Alan, Yamaguchi Terry P
Abstract excerpt
The alignment of the left-right (LR) body axis relative to the anteroposterior (AP) and dorsoventral (DV) axes is central to the organization of the vertebrate body plan and is controlled by the node/organizer. Somitogenesis plays a key role in embryo morphogenesis as a principal component of AP elongation. How morphogenesis is coupled to axis specification is not well understood. We demonstrate that Wnt3a is...
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