Article
Tsix-mediated repression of Xist accumulation is not sufficient for normal random X inactivation.
Human molecular genetics - 15 Jun 2001
Morey C, Arnaud D, Avner P, Clerc P
Abstract excerpt
During the X inactivation process, one X chromosome in each female embryonic cell is chosen at random to become coated by Xist RNA and silenced. Tsix, a transcript anti-sense to Xist, participates in the choice of the inactive X and in Xist regulation through as yet unknown mechanisms. Undifferen...
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